Hello. This is Tenmei Watanabe from Clear File Seito Medical School. This is an article about my research results regarding hyperhidrosis. Hyperhidrosis is a disease that causes excessive sweating all over the body, limbs, etc. Working in sweat is definitely not hyperhidrosis, so be sure to check it out! !
First, let's look into heat rash, hidradenitis suppurativa, armpits, and anhidrosis, which are diseases that produce sweat similar to hyperhidrosis. I would like to look into family medicine, a medical strategy book that is too thick for elementary school students and cannot be compared to game strategy books.
<<Prickly heat: Similar disease: Not an autoimmune disease>>
Sweat glands are most active in infants. It occurs when the outlet of the eccrine glands that regulate body temperature become clogged due to heat and humidity.
<<Hidradenitis suppurativa: Similar disease: May be an autoimmune disease>>
It occurs when the sweat glands become suppurated. It will heal once the pus comes out.
<<Armpit: Similar disease: Not an autoimmune disease>>
Refers to smelly sweat in the armpits. It is caused by a mixture of bacteria on the skin and sweat.
<<Anhidrosis: Similar diseases>>
Sweat may not be produced in one part of the body, or the whole body may not produce sweat. The inability to sweat is caused by abnormalities in the eccrine glands that regulate body temperature or the nerves related to the eccrine glands.
Let's look at the commonalities of heat, tension, high fever, Graves' disease, and diabetes, which are secondary diseases of hyperhidrosis.
<<Graves' disease: Secondary disease: Autoimmune disease>>
Symptoms include swelling of the thyroid gland, palpitations, and facial changes such as eyes protruding. It also makes you sweat. Antibodies are produced that bind to thyroid-stimulating hormone receptors and stimulate the thyroid gland. Graves' disease is an autoimmune disease that causes abnormalities in immune function.
<<Diabetic neuropathy: secondary disease, autonomic imbalance>>
In diabetic neuropathy, problems occur in peripheral nerves that spread throughout the body. Damage to the autonomic nervous system causes symptoms such as abnormal sweating. The cause is that sorbitol, which is converted from excessive glucose intake, accumulates in nerve cells, or that end products of glycation accumulate. Treatment drugs include aldose reductase inhibitors.
Based on the conclusion so far, I feel that the idea that hyperhidrosis is due to autonomic nervous system imbalance is the closest to the answer. Graves' disease is also an autoimmune disease, but if it is related to autonomic nervous system imbalance, we can see that they are both secondary to hyperhidrosis and are the cause of the same disease.
★Confirmed tasks and assumptions below★
(★Task 1) Investigate heat rash, hidradenitis suppurativa, armpits, and anhidrosis
(★Task 2) Investigate heat rash, tension, high fever, and anhidrosis, which are secondary diseases of hyperhidrosis. Find commonalities between Graves' disease and diabetes
(★Hypothesis 1) Perhaps some kind of chemical substance, such as heat or stress, is being released.
(★Hypothesis 2) Hyperhidrosis is not an autoimmune disease but an autonomic nervous disorder.
☆The following are unconfirmed issues and assumptions☆
(Assignment 3) One of the treatments is to cut the sympathetic nerves in the armpits, so let's research this
(Assignment 4) Research the sweat glands and eccrine glands in Wiki and medical books
( Question 5) What is the difference between peripheral nerves and autonomic nerves?
(Question 6) What is the relationship between foods containing a lot of sorbitol and diseases related to hyperhidrosis and autonomic imbalance? Find out about aldose reductase inhibitors
(Point 1) Abnormalities in the eccrine glands that regulate body temperature and the nerves that connect to the nerves
(Point 2) Graves' disease is an autoimmune disease, and are related diseases also autoimmune diseases
(Look it up on Wiki) Hyperhidrosis syndrome, prickly heat, hidradenitis suppurativa, armpits, anhidrosis, Graves' disease, diabetes, sweat glands, eccrine glands
(hypothesis 3) Diabetic neuropathy causes damage to peripheral nerves, and one of the symptoms is abnormal sweating. Hyperhidrosis may also be caused by a problem with peripheral nerves.