Sunday, April 21, 2024

Read the textbook starting from the parts that interest you. Then teach what you learned to someone online! by Nada 20231108

Hello. This is Nada from Seito Medical School. When reading a textbook or reference book, do you read it in order from beginning to end? I recommend reading the textbook starting from the parts that interest you. If you look at the first table of contents, it should give you a rough idea of ​​what's on each page. I think that the order in which you read a book doesn't matter as long as you end up looking through all the pages. Follow your own curiosity. Textbooks and reference books that you must have picked up because you were at least interested in them. If you prioritize what you are most interested in, you will be able to absorb knowledge more efficiently.


Or, if you have a purpose in mind at the beginning, such as wanting to research something, you will be able to enjoy your time more deeply. What do you want to research and what do you want to know? Students at universities that are research institutions definitely need to be aware of these issues. Of course, I think it's worth being aware of for junior high and high school students as well.


Read books in a way that immerses you in line with your own intellectual curiosity. That's the fastest way to acquire knowledge. If you teach others, which is said to be the most effective way to learn, your retention of knowledge will be much higher. I also like to write down whatever comes to mind at the beginning of the day, even if it's just like prose. What do you want to learn in the process, and what kind of schedule will you use to accomplish it? I think it's best to first understand the overall picture to some extent, and then narrow down your focus and learn from there. The theme this time was that the most efficient way to learn knowledge is to read from the parts that interest you, without worrying about the order in which you read them. See you soon.

Disassemble cars and extract natural resources. If we can turn it into a successful business, we could become a resource-rich nation. by Nada 20231108

Hello. This is Nada from Seito Medical School. This time, it's about surplus resources. When you think of natural resources, you probably think of manufacturing materials that come from coal mines, such as ores and rare earths. I think there are many different kinds of resources, but I think natural resources are an important element that is essential for manufacturing. When most people think of rare metals, they probably think of new metals extracted from mines and used as materials for cars and other products.


Here's what I want to say. The question is whether the natural resources really need to be new. If you think about it, there are a variety of second-hand items, from books to games to clothes. However, I have never heard of second-hand products made from natural resources. Of course, recycling aluminum and steel cans is a natural resource for second-hand goods, but... Even if it is a natural resource, if something made from it is thrown away, it becomes garbage that cannot be decomposed naturally. Previously, there was a problem with large amounts of plastic straws being thrown into the ocean, but it takes a lot of effort to dispose of even one car. However, the amount of natural resources that can be extracted from a single car is by no means small.


Cars are exported from wealthy countries to less wealthy countries as used cars, but I don't think many people know what happens to those used cars at the end. I am one of them and don't know what will happen in the end. Therefore, there is a need for a business that specializes in dismantling used cars with specialized equipment. I've heard of the used car dismantling business, so exported used cars may end up being dismantled somewhere. Therefore, if there were a company that specialized in dismantling used cars and extracting natural resources, Japan could become a resource powerhouse even if there were no mines in the country to mine new natural resources.


I think it will be important in the future to be able to recycle resources. The recycling situation itself will have an impact on the global environment for centuries to come. It can be said that this is a very important social issue.

The prime number formula is here! ! axa-bxb-cxc is a 3mod4 prime number formula! ? By the way, axa+bxb is a prime number expression of 1mod4

Hello. This is Watanabe Tenmei from Seito Medical School Clear File. This time, I'm going to talk about prime numbers, and I might have found the formula for prime numbers.


The first expression that comes to mind for prime numbers is the expression a^2+b^2. By the way, a^2 means multiplying a twice, and a^3 means multiplying a three times.


I have long suspected that a^2-b^2-c^2 is a prime number formula. I couldn't say for sure, so I felt confused.


The formula a^2+b^2 yields all 1mod4 prime numbers. However, the prime number of 3mod4 does not come out. By the way, 1mod4 means that the remainder when divided by 4 is 1, and 3mod4 means that the remainder when divided by 4 is 3.


The reason why only 1mod4 comes out is that when you substitute 0, 1, 2, and 3 for a^2, 0^2=0, 1^2=1, 2^2=4, 3^3 =9. If we look at the mod4, or the remainder when divided by 4, we get 0mod4, 1mod4, 0mod4, and 1mod4.


We have looked at numbers 0, 1, 2, and 3 in order, but in the subsequent numbers 4, 5, 6, and 7, their square mod4 is 0, 1, 0, 1. If you mod4 these 4, 5, 6, 7, or any subsequent numbers, they will become 0mod4, 1mod4, 2mod4, or 3mod4, so their squares are 0mod4, 1mod4, 0mod4, and 1mod4, respectively.


Since a^2 mod4 is 0 or 1, a^2+b^2 is either (0+0), (0+1), (1+0), or (1+1). In fact, this is one of 0, 1, or 2, so it will be anything other than 3. By the way, 4 is 0mod4, so 4 and 0 are the same mod4, 0mod4 as a remainder when divided by 4.


In other words, a^2+b^2=3mod4 does not exist. At least for integers.


So, let's change the sign of a^2+b^2. a^2 – b^2 is the product of all composite numbers, that is, the product of multiplication. A prime number is a number that is only divisible by itself, such as 2, 3, 5, and 7, but a composite number can be said to be the product of two or more integers such as 5×3 or 5×7, such as 15 or 35. .


Here, since a^2 – b^2=(a+b)(ab), there are conditions, but all composite numbers will come out. The condition is that when the difference between a and b is 1, a prime number may appear, for example 4^2- 3^2 = 7. If the difference between a and b is 2 or more, and both a and b are integers that are not 0, a composite number will appear.


For example, 5^2 – 3^3 = 16, 7^2 – 2^2 = 45.


Earlier, we reversed the sign of the first equation a^2 + b^2 from + to - as a^2 – b^2, but if we change the sign, we will get the opposite value. For example, if you change 4a+1 to 4a-1, 4a+1=1,5,9,13,17,21,... and 4a-1=3,7,11,15,19,23,... Odd numbers that did not exist in 4a+1 will now appear in 4a-1.


So far, a^2+b^2 includes all prime numbers of 1mod4, and a^2-b^2 includes all composite numbers, although there are conditions. While a^2 – b^2 was a composite number, by reversing its sign, a prime number of 1mod4 appears, which is the opposite of a composite number.


So, even though we inverted the formula for the composite number by changing its sign, why doesn't the formula for the prime number 3mod4 still come out? This is because the sign of b^2 has changed between a^2 – b^2 and a^2 + b^2, but the sign of a^2 has not changed.


If we change the formula for the composite number of a^2 – b^2 to the formula for the prime number of a^2+b^2 which is 1mod4, and then change the sign of a^2, we get -a^2+b^2. , is essentially the same as the formula for a^2-b^2. However, if you change the sign of a^2 and b^2 from + to -, it becomes - a^2 – b^2, which becomes a negative value.


In other words, from the relationship of only a^2 and b^2, there is no prime number of 3mod4.


Then what should we do. Here, let's reverse the expression for a composite number, not by its sign, but by whether it is a prime number or a composite number. a^2 – b^2 Since b^2 is a composite number, let's replace b^2 with a prime number p. a^2- p Now, for this expression to be an odd prime number, a^2 must be 0mod4.


In other words, if you subtract the prime number of 1mod4 or the prime number of 3mod4 from 0mod4, 0mod4-1mod4=3mod4, 0mod4-3mod4=1mod4. By the way, 0mod4-1mod4 is 3mod4, but it is essentially the same as mod4, and when divided by 4, -1mod4=3mod4=7mod4, etc.


Here, we want to obtain a prime number of 3mod4, so by substituting the prime number formula of 1mod4, that is, b^2+c^2, to p of a^2 – p, we obtain a prime number of a^2 – p = 0mod4 – 1mod4 = 3mod4. Masu. The reason why a, b, and c are interchanged is because a^2+b^2 and b^2+c^2 are essentially the same addition of squares. As long as other people can see it and the same alphabets don't overlap, there's no problem in changing it around.


By the way, a^2+b^2 and a^2-b^2 are essentially addition and subtraction, so please be careful about that.


Now, if we substitute b^2+c^2 for p, we get a^2 – (b^2 + c^2). Expanding the formula, we get a^2 – b^2 – c^2, which is the prime number formula mentioned at the beginning. By the way, a^2 must be 0mod4 and a is an even number. b^2+c^2 is essentially the same because the combination of b and c is even and odd or odd and even. In other words, 0mod4+1mod4, so if b^2+c^2 is fixed as an even number and an odd number, a^2 – b^2 – c^2 = even number^2 – even number^2 – odd number^2.


Even numbers can be expressed as 2a and 2b, and odd numbers can be expressed as 2c+1, so it becomes (2a)^2-(2b)^2-(2c+1)^2, which is the prime number expression of 3mod4. Since the prime number expression of 1mod4 is a^2+b^2, we can now express the expression of the prime number of 1mod4 and the prime number of 3mod4, that is, all prime numbers. By the way, let's leave the prime number 2 alone.


Friday, April 19, 2024

Cure Parkinson's disease! ? Relationship between REM sleep and schizophrenia

Hello. This is Tenmei Watanabe from Seito Medical School. This time, it's a continuation of Parkinson's disease. Let's proceed by assuming that Parkinson's disease is NREM sleep and schizophrenia is REM sleep.


In the previous article, we showed that Parkinson's disease is characterized by low blood pressure, hypothermia, and parasympathetic predominance. In fact, during sleep, during non-REM sleep, the parasympathetic nervous system is dominant, and body temperature tends to be lower than when awake, and many similarities can be found between Parkinson's disease and non-REM sleep.


On the other hand, schizophrenia has high blood pressure and high body temperature, and is dominated by the sympathetic nervous system. Even during REM sleep, when you dream, your body temperature is higher than during non-REM sleep, and the sympathetic nervous system is dominant, so you can say that you are in a state of tension.


The heart rate is high during REM sleep, and it is also high in schizophrenia, but this state of high body temperature and high heart rate is very important when symptoms of schizophrenia such as hallucinations and auditory hallucinations occur. This is an important factor.


In other words, the state of dreaming is accompanied by hallucinations and auditory hallucinations, and it is the difference between being awake and dreaming, and sleeping and dreaming.


Febrile delirium, which causes symptoms such as hallucinations due to high fever, also occurs when the body temperature is high and the heart rate is high. Furthermore, when smoking cannabis, there is a noticeable increase in heart rate, and in severe cases, symptoms such as hallucinations appear.


Schizophrenia, fever delirium, and drug addiction all cause similar symptoms such as hallucinations due to increased heart rate and large amounts of dopamine released.


During REM sleep, your heart rate and breathing rate increase, and your breathing becomes shallow. This is exactly the reaction when the sympathetic nervous system is dominant.


During non-REM sleep, heat release increases, sweating occurs, and body temperature decreases. It can be said that this is when the parasympathetic nervous system is dominant.


Activities that release dopamine include eating sugar, staying up all night, and meditating. There is no problem if taken in moderation, but if these are combined, symptoms of schizophrenia may appear.


These actions increase your heart rate and raise your blood pressure. In other words, the sympathetic nervous system is dominant.


When the sympathetic nervous system becomes dominant, cardiac muscle contraction increases, heart rate increases, and peripheral nerves throughout the body contract. When the parasympathetic nervous system is dominant, the opposite effect occurs.


There is a heart in the heart. In the past, people believed that the heart was in the heart. In modern times, it is common knowledge that humans use their brains to think and feel things.


However, heart rate and even blood flow may control human sensations. When the heart rate increases and blood flow increases, the metabolism of various substances in the body becomes active. It may be said that the reason why something that does not normally exist in front of our eyes appears in front of our eyes as a hallucination depends on the blood flow rate of the heart.


On the other hand, Parkinson's disease is exactly the opposite of schizophrenia, so it may be a good idea to think about what I have described so far in the opposite way.


Parkinson's disease has the same symptoms as non-REM sleep, with low blood pressure and low heart rate dominated by the parasympathetic nervous system. There is also less blood flow, so as mentioned in the previous article, you will probably experience symptoms such as trembling in your hands in response to the cold.


Furthermore, if you explore the information that the amygdala becomes active during REM sleep and its relationship with peripheral nerves, you may come across some interesting facts.


I would like to explore this area as a future issue. It may be possible to broadly divide diseases and diseases into two types based on whether the sympathetic nervous system is dominant or the parasympathetic nervous system is dominant. that's all. See you soon.


Symptoms of Parkinson's disease are the same as reactions to cold weather in winter! ?

Hello. This is Tenmei Watanabe from Seito Medical School. This time, as a medical school report, I would like to research Parkinson's disease and its treatment methods.


Parkinson's disease presents with movement disorders, such as tremors in the hands and difficulty moving or walking. Although it is considered to be a progressive neurodegenerative disease, onset is most common in middle-aged people over 40 years of age, especially in people over 65 years of age. (Quoted from Family Medicine)


Some of the symptoms of Parkinson's disease are similar to how humans react to the cold in winter.


In Japan, it is said to be caused by damage to dopamine neurons in the substantia nigra. Conditions other than Parkinson's disease that have similar symptoms are called Parkinson's syndrome. Dementia often develops as a secondary disease to Parkinson's disease.


Parkinson's disease is a disease caused by a lack of dopamine, and schizophrenia is a disease caused by an excess of dopamine.


Let's make an assumption here.


Hypothetically, a deficiency in metabolism is associated with Parkinson's disease, and an increased metabolism is associated with schizophrenia. In other words, it can be divided into Parkinson's disease, which is dominated by the parasympathetic nervous system, and schizophrenia, which is dominated by the sympathetic nervous system.


Parkinson's disease causes low blood pressure, low body temperature, and poor metabolism. I have symptoms similar to a reaction to enduring the winter cold, and I don't sweat enough. Blood vessels dilate, body temperature falls, and because the parasympathetic nervous system is dominant, patients often have problems such as frequent urination.


Parkinson's disease symptoms are caused by an illusion of thermoregulation, such as the winter cold. Because there is not enough amino acids, there is no metabolism and body temperature does not rise.


On the other hand, people with schizophrenia have high blood pressure, high body temperature, and a fast metabolism. My mental health often worsens in the summer, and I sweat excessively. Blood vessels constrict, body temperature rises, and the sympathetic nervous system predominates. The positive symptoms of schizophrenia correspond to manic depression, and the negative symptoms correspond to depression. The difference is whether there are temporary stable symptoms.


"In some cases, dementia affects the autonomic nervous system that regulates sweating and blood volume, making it difficult to regulate body temperature. For example, in Lewy body dementia (*1), symptoms include excessive sweating, night sweats, and dilated blood vessels in the skin. However, increased sweat and blood flow unrelated to ambient temperature can lower body temperature and cause hypothermia.


(https://www.citizen-systems.co.jp/health/column/article/article_10.html)


The above quotation is consistent with the vasodilation and hypothermia of Parkinson's disease, and the symptoms of Parkinson's disease patients include excessive sweating in the upper body and less sweating in the lower body, so it may be similar to Lewy body dementia. seems to be related to abnormalities in the autonomic nervous system.


The future challenge is to explore the possibility of Parkinson's disease from the negative side of schizophrenia and the positive side of dementia, which are the opposite of Parkinson's disease.


The cause of hyperhidrosis was a disturbance in the autonomic nervous system! ? The key is sorbitol, which is a form of glucose! !

Hello. This is Tenmei Watanabe from Clear File Seito Medical School. This is an article about my research results regarding hyperhidrosis. Hyperhidrosis is a disease that causes excessive sweating all over the body, limbs, etc. Working in sweat is definitely not hyperhidrosis, so be sure to check it out! !


First, let's look into heat rash, hidradenitis suppurativa, armpits, and anhidrosis, which are diseases that produce sweat similar to hyperhidrosis. I would like to look into family medicine, a medical strategy book that is too thick for elementary school students and cannot be compared to game strategy books.


<<Prickly heat: Similar disease: Not an autoimmune disease>>

Sweat glands are most active in infants. It occurs when the outlet of the eccrine glands that regulate body temperature become clogged due to heat and humidity.


<<Hidradenitis suppurativa: Similar disease: May be an autoimmune disease>>

It occurs when the sweat glands become suppurated. It will heal once the pus comes out.


<<Armpit: Similar disease: Not an autoimmune disease>>

Refers to smelly sweat in the armpits. It is caused by a mixture of bacteria on the skin and sweat.


<<Anhidrosis: Similar diseases>>

Sweat may not be produced in one part of the body, or the whole body may not produce sweat. The inability to sweat is caused by abnormalities in the eccrine glands that regulate body temperature or the nerves related to the eccrine glands.


Let's look at the commonalities of heat, tension, high fever, Graves' disease, and diabetes, which are secondary diseases of hyperhidrosis.


<<Graves' disease: Secondary disease: Autoimmune disease>>

Symptoms include swelling of the thyroid gland, palpitations, and facial changes such as eyes protruding. It also makes you sweat. Antibodies are produced that bind to thyroid-stimulating hormone receptors and stimulate the thyroid gland. Graves' disease is an autoimmune disease that causes abnormalities in immune function.


<<Diabetic neuropathy: secondary disease, autonomic imbalance>>

In diabetic neuropathy, problems occur in peripheral nerves that spread throughout the body. Damage to the autonomic nervous system causes symptoms such as abnormal sweating. The cause is that sorbitol, which is converted from excessive glucose intake, accumulates in nerve cells, or that end products of glycation accumulate. Treatment drugs include aldose reductase inhibitors.



Based on the conclusion so far, I feel that the idea that hyperhidrosis is due to autonomic nervous system imbalance is the closest to the answer. Graves' disease is also an autoimmune disease, but if it is related to autonomic nervous system imbalance, we can see that they are both secondary to hyperhidrosis and are the cause of the same disease.


★Confirmed tasks and assumptions below★

(★Task 1) Investigate heat rash, hidradenitis suppurativa, armpits, and anhidrosis

(★Task 2) Investigate heat rash, tension, high fever, and anhidrosis, which are secondary diseases of hyperhidrosis. Find commonalities between Graves' disease and diabetes

(★Hypothesis 1) Perhaps some kind of chemical substance, such as heat or stress, is being released.

(★Hypothesis 2) Hyperhidrosis is not an autoimmune disease but an autonomic nervous disorder.


☆The following are unconfirmed issues and assumptions☆

(Assignment 3) One of the treatments is to cut the sympathetic nerves in the armpits, so let's research this

(Assignment 4) Research the sweat glands and eccrine glands in Wiki and medical books

( Question 5) What is the difference between peripheral nerves and autonomic nerves?

(Question 6) What is the relationship between foods containing a lot of sorbitol and diseases related to hyperhidrosis and autonomic imbalance? Find out about aldose reductase inhibitors

(Point 1) Abnormalities in the eccrine glands that regulate body temperature and the nerves that connect to the nerves

(Point 2) Graves' disease is an autoimmune disease, and are related diseases also autoimmune diseases

(Look it up on Wiki) Hyperhidrosis syndrome, prickly heat, hidradenitis suppurativa, armpits, anhidrosis, Graves' disease, diabetes, sweat glands, eccrine glands

(hypothesis 3) Diabetic neuropathy causes damage to peripheral nerves, and one of the symptoms is abnormal sweating. Hyperhidrosis may also be caused by a problem with peripheral nerves.

You may freely copy and paste articles from this blog as long as you provide a link

Hello. This is Tenmei Watanabe from Seito Medical School. Below is the pre-rewrite article.



plagiarism. Sometimes it makes the news. A university professor cheated on his thesis. If he sees a similar article on his blog, he may suspect plagiarism. Fortunately, I have probably never been plagiarized until now.


I think many people feel angry when they find out that their work has been plagiarized. I also don't feel at ease when someone uses my articles as their own, even though I didn't give them permission. However, not many people have ever thought about the psychology of those who plagiarize.


If it's a blog, it's plagiarism, so at least people are reading my blog. On top of that, the people who plagiarize can be said to be fans of the content of the people whose content is being plagiarized, because the plagiarized articles are so attractive that they are willing to take the risk to use them without permission.


Here, you can see that instead of talking about plagiarism as a story about something bad done, it is better to guide the plagiarism in a good way as a colleague. For example, if you discover that your work has been plagiarized, you can contact the person who plagiarized the work and ask them to link to your site.


If you have any other concerns, please feel free to point them out and have them improve. For example, if you tell them that it's okay to copy and paste, but not to modify, there's a good chance they'll restore the changes you made. Since there is a link on it, if you think that it is working for advertising, it will be beneficial for you as well.


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If you were to plagiarize, who would you plagiarize from? It's human nature to want to plagiarize content from someone you admire who creates content you like.


Therefore, instead of making unnecessary trouble, if you give them permission to use the game as long as they follow the rules, like a franchise, you can prevent them from losing their precious core fans.


I will claim copyright on this blog, but as long as you post a link, I don't mind people copying and pasting it without my permission. This is because, although I may try it out, I would like to attract customers with my blog and sell e-books, USB memory, etc., rather than posting advertisements and earning income.


The only cost for e-books is the electricity bill and a certain percentage of the fees, so I think it would be okay to sell them for 400 yen or something. Many USB flash drives can now be purchased for less than 1,000 yen, and I would like to sell it for less than 2,000 yen including shipping.


As those who read this blog will understand, my blog seems to contain a large amount of information, and is like a large burger. The prices for e-books and USB memory are unbeatable, so I would like to include useful data.


As long as I know that I am the author, I don't mind if other people copy and paste my articles on their blogs. Of course, as I have said repeatedly, I would like you to be sure to link to our blog.


As long as you post a link, you can of course tell me about it, but I don't think it's a problem if people copy and paste articles from this blog onto other sites without my permission.


In this blog called Seito Medical School Clear File, I'm going to write that you can copy and paste it anywhere you can see it in the blog, so please use it if you like.



This time it was a rewritten article, but it was about my recent movements. If you are having trouble selling USB memory, I would be grateful if you could give me some advice. It would be good if we could separate the cases by selling USB memory by mail to people living in Japan, and e-books to people living overseas.


That's all about my ideas for now. Let's meet again! ! See you soon.


When making a proposal to your boss, take his or her opinion into account! Your opinions and positions become more important. 230111

  Hello. This is Inishitenmei from Seito Juku. This time, we will talk about how to get other people to join in. What do you do when you wan...